Fig 1: Protein expression of ICP0 (A,B), HMG I/Y (C,D), and TDP43 (E,F) during 10 h of HSV-1 KOS and HSV-1 n212 productive infection in primary adult DRG neuronal cultures, with or without MG132 to inhibit proteasomal degradation. Neurons were assessed every 2 h by Western blot (n = 3), analyzed by densitometry, and normalized to total protein visualized with TCE. Representative Western blots are shown (G). Error bars = SD. Horizontal bars indicate statistical significance between MG132 treated and untreated (A,C) or between 0 h and 2 h and UI (E,F) (p < 0.05). Asterisks indicate statistical significance between KOS- and n212-infected neurons (p < 0.05).